Located in a very central position in the heart of Rome near the most famous shopping streets, the HO Maison de Luxe is located in a restricted traffic area, thus far from the chaos typical of large cities.

The Spanish Steps, Trinità dei Monti, the Sallustiano obelisk, the Trevi Fountain, Villa Borghese and Piazza del Popolo are within easy walking distance.

In the vicinity, besides the well-known wonders of Rome, there is a wide range of:
- Theaters and museums, such as the Sistina Theater, the Salone Margherita and the Borghese Gallery and Museum, Keats & Shelley's House, the Modern Art Gallery of Rome.
- Basilicas and palaces of historical interest, such as Palazzo del Quirinale, Villa Medici, Palazzo Barberini, Tea Room's Babbington and the Convent of the Cappuccini in Via Veneto, the Church of Trinità dei Monti, the Church of Sant'Andrea delle Fratte, the Hertziana library of Palazzo Zuccari.